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Secarna Pharmaceuticals publishes new preclinical data in The Journal of Immunology demonstrating potent therapeutic activity of LNAplus™ ASO targeting NLRP3 in highly debilitating autoinflammatory diseases

  • Secarna's LNAplus™ ASOs suppress expression of NLRP3, a central component of the inflammasome pathway, which is overactive in many inflammatory diseases
  • Cryopyrin-associated periodic syndrome (CAPS) is a group of rare inherited autoinflammatory diseases driven by overactive NLRP3, resulting in systemic inflammation
  • With NLRP3-specific ASOs, inflammatory downstream effects were interrupted in immune cells and strong symptom relief and significant prolongation of survival was achieved in a CAPS disease model.

More Articles ...

  1. AR43's Commitment To Compassionate Spaces Expands With A New Community Project
  2. Three HKUMed scholars acquire international accolades
  3. YA-MAN Becomes the First Brand of Home-use Beauty Devices to Attend the World Congress of Dermatology
  4. Amazon Singapore Unveils the Real Deals this Prime Day with Epic Discounts and Great Savings
  5. KDDI Digital Life, Japan’s digital telco, achieves high customer satisfaction score with Circles
  6. Gentari and Keppel team up to expand sustainable energy solutions in Southeast Asia
  7. DPR Asia Pacific joins the United Nations Global Compact Initiative
  8. GEODIS recognized as "Best Companies to Work for in Asia" for second year, and receives the "Diversity, Equity & Inclusion" Award
  9. 2023 Global Esports Summit Agenda Revealed: More than 30 Global Guests Will Discuss New Developments in Esports
  10. Spackman Media Group Artist Son Suk-Ku’s Upcoming Highlight Anticipated Netflix Original Drama, D.P. Season 2, Premieres on July 28
  11. HKU Partnership for Sustainability Leadership in Business Hosts Knowledge Primer 5 cum Sustainable Value Chains Commitment and SMEs Sustainability Leadership Recognition Awards Ceremony
  12. ATFX Expands its Global Reach with Acquisition of Rakuten Securities Australia
  13. Docomo Business Hong Kong’s first end-to-end Managed Private 5G service to help enterprises unlock their potential with new mmWave technology
  14. CloudMile Announces Strategic Partnership With Fivetran
  15. The wait is over: marking BTS’ 10th anniversary opens in Thailand in August, first in SouthEast Asia
  16. Johannesburg Prepares for Highly Anticipated Digital Finance Africa 2023
  17. VERTU Unveils Global Duty-Free Store Strategy with new opening in SANYA
  18. Samsung Partners International Olympic Committee to Present Inaugural Olympic Esports Week in Singapore
  19. WRISE Group Accelerates Business Momentum with Expansion of Business Footprint and Leadership Capabilities
  20. TUMI Launches Immersive Essentially Beautiful Pop-Up in Seoul

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