Business Daily Media

Men's Weekly

.

Blood vessel-forming cells involved in aggressive brain tumour

  • Written by ACN Newswire
Blood vessel-forming cells involved in aggressive brain tumour
Selangor, Malaysia, June 20, 2018 - (ACN Newswire) - A type of highly malignant brain tumour contains a large number of cells involved in the formation of new blood vessels, helping it proliferate and spread. Targeting these cells could hinder tumour growth, according to new research published in the Pertanika Journal of Science & Technology.

Astrocytomas are tumours that can be found in the brain and spinal cord and originate from a type of cell, called an astrocyte, whose main function is to insulate and to provide structure for nerve fibres. They are the most common type of tumour that originates in the brain. There are four grades of astrocytomas, ranging from least to most aggressive. Grade IV astrocytomas are highly invasive and are almost always fatal. Lower grade astrocytomas are typically found in younger people while higher grade tumours are more often found in older adults.

Astrocytomas depend on new blood vessel formation to grow and spread. Researchers in Malaysia wanted to know how the numbers of 'endothelial progenitor cells' (EPCs), which play a role in new vessel formation, changed with increasing grades of astrocytoma. EPCs represent a variety of cell types that circulate in the blood and adhere to the inner linings of blood vessels.

The team of scientists examined brain tissue from 22 astrocytoma patients at the Hospital of University Sains Malaysia. They found that the numbers of endothelial progenitor cells were higher in the tumours than they were in surrounding healthy tissue. They also found that the numbers of these cells inside tumour tissue increased with age and higher tumour grade.

Previous research has shown that patients with grades III and IV astrocytomas who underwent radiotherapy or chemotherapy demonstrated a reduction in the numbers of circulating EPCs. People with grades III and IV astocytomas who didn't undergo treatment had higher numbers of circulating EPCs than healthy people.

Other studies have also shown that significantly reducing EPCs led to impaired and delayed growth in tumours followed by a reduction in the numbers of blood vessels feeding them.

The researchers conclude that their findings suggest that drugs targeting new blood vessel formation given in appropriate doses according to age and tumour grade could prevent astrocytoma growth.

For more information, contactPriscilla DasSchool of Medical Sciences,Universiti Sains MalaysiaEmail: [email protected][1]; [email protected][2]

About Pertanika Journal of Science & Technology (JST)Pertanika Journal of Science & Technology (JST) is published by Universiti Putra Malaysia in English and is open to authors around the world regardless of nationality. Currently, it is published twice a year in January and July. Other Pertanika series include Pertanika Journal of Tropical Agricultural Science (JTAS), and Pertanika Journal of Social Sciences & Humanities (JSSH). Website: http://www.pertanika.upm.edu.my/[3]

Pertanika Journal of Science & Technology aims to provide a forum for high quality research related to science and engineering research. Areas relevant to the scope of the journal include: bioinformatics, bioscience, biotechnology and bio-molecular sciences, chemistry, computer science, ecology, engineering, engineering design, environmental control and management, mathematics and statistics, medicine and health sciences, nanotechnology, physics, safety and emergency management, and related fields of study.

Research paper: https://bit.ly/2trEA3N[4]

For more information about the journal, contact:The Chief Executive Editor (UPM Journals)Office of the Deputy Vice Chancellor (R&I)IDEA Tower 2, UPM-MDTC Technology CentreUniversiti Putra Malaysia43400 Serdang, SelangorMalaysia.Phone: +603 8947 1622 | +6016 217 4050Email: [email protected][5]

Distributed for Pertanika Journal of Science & Technology by ResearchSEA.

Topic: Research and developmentSectors: Nanotechnology, BioTech, HealthCare[6][7][8] http://www.acnnewswire.com From the Asia Corporate News Network

Copyright © 2018 ACN Newswire. All rights reserved. A division of Asia Corporate News Network.

References

  1. ^ [email protected] (www.acnnewswire.com)
  2. ^ [email protected] (www.acnnewswire.com)
  3. ^ http://www.pertanika.upm.edu.my/ (www.pertanika.upm.edu.my)
  4. ^ https://bit.ly/2trEA3N (bit.ly)
  5. ^ [email protected] (www.acnnewswire.com)
  6. ^ Nanotechnology (www.acnnewswire.com)
  7. ^ BioTech (www.acnnewswire.com)
  8. ^ HealthCare (www.acnnewswire.com)

Read more http://www.acnnewswire.com/press-release/english/44192/

Workplace DMs, Reinvented: Deputy Messaging, Purpose-Built For Shift-Based Teams

Deputy, the global people platform for shift-based businesses, has launched Deputy Messaging, a fully integrated, real-time communication tool designe...

Revolutionizing Fulfillment: How Virtual Warehousing is Changing the Game?

The e-commerce landscape is evolving more rapidly than ever, and the way businesses are managing their fulfillment is also revolutionizing. At the...

SME lender Dynamoney welcomes new CEO, Brett Thomas

Strengthens growth ambitions and signals expanded offering Dynamoney, a leading commercial finance provider for Australian SMEs,  has today appoint...

The cost of ignoring AI governance in business

Artificial intelligence (AI) is no longer the promise of a distant future: it's active, embedded, and already shaping decisions across industries. H...

Quickli launches new SMSF product as free beta for limited time only

The leading technology provider for Australian mortgage brokers, Quickli, has answered the prayers of brokers yet again with the launch of a stand...

Portable Monitors for Coding and Programming Students

Today, coding and programming require more focus and efficiency. But, the most essential thing it demands is ample screen space. Students can stru...

Sell by LayBy