Business Daily Media

Men's Weekly

.

Base Therapeutics announces the completion of its A2 round of financing

Base Therapeutics' AccuBase® Base Editor Receives Overseas Patent Authorization

HONG KONG SAR - Media Outreach Newswire - 12 September 2024 - Base Therapeutics recently announced the completion of its A2 round financing, raising tens of millions of RMB.

This round of financing was led by AEF Greater Bay Area Fund, managed by Gobi Partners GBA and will be used to strengthen Base Therapeutics' R&D team, optimize its product pipeline, accelerate clinical trials, and pave the way for future commercialization. Additionally, the company plans to establish a presence in the Greater Bay Area, with Hong Kong as its core, to support internationalization efforts, continuous R&D, innovation, and international cooperation and exchange activities.

(Base Therapeutics and Gobi Partners GBA signed an MOU at the Belt and Road Summit to support Base Therapeutics’ expansion into the Belt and Road market, starting with a Hong Kong operation. From left to right: Dr Grace Lau, Head of Institute for Translational Research of Hong Kong Science and Technology Parks Corporation, Mr Charles Ng, Associate Director-General of InvestHK, Dr Tianhong Xu, founder and CEO of Base Therapeutics, Mr Fred Li, Senior Executive Director of Gobi Partners GBA, Mr Nicholas Ho, Commissioner for Belt and Road of The Government of the Hong Kong Special Administrative Region of the People
(Base Therapeutics and Gobi Partners GBA signed an MOU at the Belt and Road Summit to support Base Therapeutics’ expansion into the Belt and Road market, starting with a Hong Kong operation. From left to right: Dr Grace Lau, Head of Institute for Translational Research of Hong Kong Science and Technology Parks Corporation, Mr Charles Ng, Associate Director-General of InvestHK, Dr Tianhong Xu, founder and CEO of Base Therapeutics, Mr Fred Li, Senior Executive Director of Gobi Partners GBA, Mr Nicholas Ho, Commissioner for Belt and Road of The Government of the Hong Kong Special Administrative Region of the People's Republic of China)

Base Therapeutics was founded in 2021 and is a technology-driven innovative enterprise focusing on foundational innovations in gene editing. It is a global pioneer in base editing and cell gene therapy research and development. Since its inception, the company has been committed to developing world-first cell therapies and gene editing products, particularly showing great promise in treating cancers and genetic diseases.

Base Therapeutics has developed a series of core technologies in the field of gene editing, including ePE lead editing, the AccuBase® base editing system, CasH gene editing technology, BEAT-CART technology, and in vivo targeted delivery technology. Among these, the AccuBase® base editing system possesses globally free-to-operate (FTO) characteristics, enabling efficient and zero-off-target gene editing both in vitro and in vivo. This is also the world's first Base Editing targeted NK cell therapy product, which uses base editing to confer target specificity to NK cells.

The company has built a nearly 2,500 square meter GMP cell production facility that meets the requirements for clinical-grade cell therapy research and production. Base Therapeutics' pipeline also includes multiple base-edited NK cell products targeting hematological malignancies and autoimmune diseases, as well as universal CAR immunotherapy products and in vivo gene editing.

In terms of external collaborations, Base Therapeutics has licensed its AccuBase® base editing technology non-exclusively to leading CAR-T cell therapy companies internationally. The company also collaborates with agricultural enterprises to develop thornless fish using base editing technology and explores applications in crop improvement and livestock genetic modification.

Base Therapeutics has cumulatively received tens of millions of dollars in seed and Series A investments, backed by top-tier international biopharmaceutical venture capital institutions. The company has won numerous honors, including second place in the national finals of the 12th China Innovation and Entrepreneurship Competition. It also holds 29 intellectual property applications covering software copyrights, utility model patents, national invention patents, PCT, and US patents.

Dr. Tianhong Xu, Founder and CEO of Base Therapeutics, expressed enthusiasm about the strategic partnership with Gobi Partners GBA. "Gobi Partners GBA's investment is a strong endorsement of Base Therapeutics' groundbreaking gene editing technology and our team's vision to revolutionize healthcare. With their deep understanding of the Greater Bay Area market and extensive global network, we are confident in accelerating our expansion into Hong Kong and beyond. This partnership is instrumental in advancing our clinical trials, forging strategic collaborations, and ultimately delivering life-changing therapies to patients worldwide."

As Fred Li, Senior Executive Director of Gobi Partners GBA noted, "Base Therapeutics is a promising investment opportunity in the Greater Bay Area. Their groundbreaking work in gene editing aligns with our focus on supporting cutting-edge healthcare technologies. We are confident that their expansion into Hong Kong will further strengthen their position in the global healthcare technology market and drive innovation."

(Visiting Base Therapeutics’ Laboratory in Shanghai. From left to right: Mr Jimmy Ng, Investment Director of Gobi Partners GBA, Prof. Xingxu Huang, co-founder and Chief Scientific Advisor of Base Therapeutics, Mr Thomas Tang, Analyst of Gobi Partners GBA, Mr Fred Li, Senior Executive Director of Gobi Partners GBA and , Dr Tianhong Xu, founder and CEO of Base Therapeutics)
(Visiting Base Therapeutics’ Laboratory in Shanghai. From left to right: Mr Jimmy Ng, Investment Director of Gobi Partners GBA, Prof. Xingxu Huang, co-founder and Chief Scientific Advisor of Base Therapeutics, Mr Thomas Tang, Analyst of Gobi Partners GBA, Mr Fred Li, Senior Executive Director of Gobi Partners GBA and , Dr Tianhong Xu, founder and CEO of Base Therapeutics)

About Gobi Partners GBA (Gobi GBA)
Gobi Partners GBA (Gobi GBA) was established in 2016 as a part of the leading Pan-Asian venture capital platform Gobi Partners. Gobi GBA is the general partner of the Alibaba Hong Kong Entrepreneurs Fund, L.P.(AEF)as well as the AEF Greater Bay Area Fund LPF, and has formed strategic partnerships with other renowned financial institutions such as HSBC and Hang Seng Bank.

As of 2023, Gobi GBA has invested in over 80 startups across the Greater Bay Area and has fostered the growth of 8 unicorns including Airwallex, Amber, Animoca Brands, GoGoX, Prenetics, and more.

About Base Therapeutics
On August 20, 2024, Base Therapeutics announced that its AccuBase® base editor has officially received authorization for two patents from the United States Patent and Trademark Office (USPTO). This marks that both of Base Therapeutics' AccuBase® technologies have secured patent protection in China and overseas markets. Base Therapeutics' strategic positioning in the gene editing field is at the forefront internationally, making it one of the biopharmaceutical companies with the most authorizations domestically and abroad.

AccuBase® Technology Highlights:

  • Extremely low off-target effects.
  • Demonstrated highly efficient and stable editing performance in various in vitro and in vivo environments.
  • The protein form of AccuBase® is commercialized, being the only available base editing protein worldwide, and comes in both research and GMP grades.
  • Has received multiple patent authorizations domestically and internationally.
  • Possesses characteristics allowing for freedom to operate (FTO) globally.
Products Developed Based on AccuBase®:
  • NK510: Editing efficiency up to 95% in primary NK cells; IND application completed in China, expected to file an IND application in the U.S. in September.
  • NK510 and NK520: Multiple Investigator Initiated Trials (IITs) conducted, preliminary safety and efficacy for solid tumors have been confirmed.
  • In the field of in vivo gene therapy, combined with Base Therapeutics' proprietary delivery system, AccuBase® achieves over 80% editing efficiency in the liver, with multiple in vivo gene therapy products under development.
Collaborations and Licensing:
  • AccuBase® has been licensed to a renowned international CAR-T company, achieving multi-million dollar upfront payments and milestone payments.
  • Beyond internal R&D, Base Therapeutics collaborates with other biopharmaceutical companies to develop cell products.
Dr. Tianhong Xu, founder and CEO of Base Therapeutics, stated: "Base Therapeutics will continue to innovate technologically and develop products to strive to become a leader in the global gene editing field, driving industry progress and bringing revolutionary treatment options to patients worldwide."
Hashtag: #BaseTherapeutics


The issuer is solely responsible for the content of this announcement.

Base Therapeutics

Base Therapeutics was founded in 2021 and is a technology-driven innovative enterprise focusing on foundational innovations in gene editing. It is a global pioneer in base editing and cell gene therapy research and development. Since its inception, the company has been committed to developing world-first cell therapies and gene editing products, particularly showing great promise in treating cancers and genetic diseases.

Base Therapeutics has developed a series of core technologies in the field of gene editing, including ePE lead editing, the AccuBase® base editing system, CasH gene editing technology, BEAT-CART technology, and in vivo targeted delivery technology. Among these, the AccuBase® base editing system possesses globally free-to-operate (FTO) characteristics, enabling efficient and zero-off-target gene editing both in vitro and in vivo. This is also the world's first Base Editing targeted NK cell therapy product, which uses base editing to confer target specificity to NK cells.

News from Asia

Skyborn enters Preferred Supplier Agreement with Fred. Olsen Windcarrier for Gennaker offshore installation vessel

Gennaker's offshore wind turbine transportation and installation will be performed by Fred. Olsen Windcarrier (Fred Olsen). Installation of 63 offshore wind turbines during 2028 i...

Cyberport Leads Nine Start-ups to Join WAIC 2025

Project from the Artificial Intelligence Subsidy Scheme Shortlisted for Top 30 of the SAIL AwardHONG KONG SAR - Media OutReach Newswire - 29 July 2025 - World Artificial Intelligence Conference 20...

Henan Meets SCO: Anyang Receives Acclaim from Media and Think Tank Guests

ANYANG, CHINA - Media OutReach Newswire - 29 July 2025 - From July 23 to 27, the Shanghai Cooperation Organization Media and Think Tank Summit was held in Henan Province. During this event, guests...

SY Holdings Establishes Singapore International Headquarters to Explore Web3.0 Ecosystem and Innovative Applications of Stablecoins

SHENZHEN, CHINA - EQS Newswire - 29 July 2025 - SY Holdings Group Limited ("SY Holdings" or the "Group," stock code: 6069.HK), an "AI + industrial supply chains" digital intelligence technology com...

LANDMARK Invites the Community to 'Find Your Chapter' and Celebrate the Love of Reading This Summer

Rediscover the Joy of Reading This Summer at LANDMARK, Featuring an Engaging Book Stop Pop-Up, Exclusive Promotional Offers, and Curated Literary Experiences for All Ages. HONG KONG SAR - Media Ou...

Seafood Expo Asia Announces Conference Program with Expert-led Sessions on Sustainability, Aquaculture, Fish Processing, Aquafeeds and Consumer Trends in Asian Market

The conference program will begin on the first day of the Expo, which runs from 10-12 September 2025 at the Sands Expo and Convention Centre in Singapore, and continue throughout the three-day even...

Suanova Information, a Yeebo’s Subsidiary, Makes Its Debut at the 2025 WAIC

Securing a Key Role in China's AI Computing Power Sector Driving Industry Innovation and DevelopmentHONG KONG SAR - Media OutReach Newswire - 30 July 2025 - Suanova Information (Shanghai) Limited ...

Storefriendly Introduces New Self-Service Storage System & IoT-Driven Smart Management — Enhanced Facilities to Meet Evolving Customer Needs

HONG KONG SAR - Media OutReach Newswire – 30 July 2025 - Storefriendly Self Storage Group has recently been honored with the prestigious "I&T Award (Hong Kong)" and "ESG Award (Hong Kong)" by ...

Kim Gan Enterprise Commemorates 24 Years in the Automotive and Industrial Supply Sector

SINGAPORE - Media OutReach Newswire - 30 July 2025 - Kim Gan Enterprise Pte. Ltd., an auto parts supplier in Singapore, is celebrating its 24th anniversary this year. Since its founding in 2001, ...

Letright Spotlighted In Nikkei Bizruptors For Revolutionizing Sustainable Luxury In Outdoor Living.

Recognition by Nikkei BizRuptors underscores Letright’s role in redefining eco-conscious luxury in global outdoor livingKUALA LUMPUR, MALAYSIA - Media OutReach Newswire - 30 July 2025 - Letright I...

Small-Business Cash-Flow Playbook 2025

An educational guide to managing ATO debt, real-time super and growth finance in Australia’s new landscape Why ATO debt just became the most expe...

Landowners Offered $30,000 Per Year for Just 1 Hectare: The Rise of 5MW Battery Projects Across Australia

In a pivotal shift reshaping Australia’s renewable energy landscape, landowners in Queensland, New South Wales, and Victoria are being offered up ...

Major national security tech alliance launches with Aerologix a founding member

Australia’s leading drone intelligence pioneer bolsters sovereign tech power Australia’s leading aerial data and drone intelligence platform, Aer...

Chris Hancock AM Honoured as 2025 Communications Ambassador

SYDNEY Chris Hancock AM, former CEO of AARNet, has been awarded the prestigious Communications Ambassador title at the 2025 Telecommunications Indus...

Baby boomers are driving development feasibility leading to larger apartments

As residential developers continue to grapple with feasibility issues on apartment projects, the sector is struggling to deliver volumes of new st...

Hays launches FY25/26 Salary Guide: ‘Salary Paradox’ deepens as pay rises fail Australians

Rising dissatisfaction with pay, progression and perks is fuelling a new wave of career change in FY25/26, as Australians demand more from employe...

Sell by LayBy